Newport Beach Gastroenterologist

Gastroenterology is the medical specialty focused on diagnosing, treating, and preventing disorders of the digestive system—including the esophagus, stomach, intestines, liver, pancreas, and gallbladder.

Advanced Digestive Health Care in Newport Beach

At IOPBM in Newport Beach, board-certified gastroenterologist Dr. Angie Sadeghi, MD, delivers evidence-based, patient-centered care for a comprehensive range of gastrointestinal (GI) conditions. Her approach integrates advanced diagnostics, precision medicine, and lifestyle interventions to address the root causes of disease and promote long-term gut health.

Comprehensive Gastroenterology Services

Dr. Sadeghi and the IOPBM team provide expert evaluation and management for a wide spectrum of digestive disorders.

Common GI Disorders Treated

Dr. Angie Sadeghi, MD, and the IOPBM team diagnose and manage a comprehensive range of gastrointestinal disorders affecting the esophagus, stomach, intestines, liver, pancreas, and gallbladder. Patients receive individualized care for both common and complex GI conditions, with a focus on evidence-based treatment, prevention, and long-term digestive health.

• Gastroesophageal Reflux Disease (GERD)
• Esophagitis
• Peptic Ulcer Disease
• Colon Polyps and Colon Cancer
• Irritable Bowel Syndrome (IBS)
• Inflammatory Bowel Disease (IBD): Crohn's Disease, Ulcerative Colitis
• Small Intestinal Bacterial Overgrowth (SIBO)
• Liver Disease: Hepatitis, cirrhosis, metabolic dysfunction-associated steatotic liver disease (MASLD)
• Pancreatic Disease
• Diverticulitis and Diverticulosis
• Celiac Disease
• Chronic Constipation
• Chronic Diarrhea
• Abdominal Pain
• Gallbladder Disease
• Gastroparesis

Diagnostic and Therapeutic Procedures

IOPBM offers advanced diagnostic and therapeutic procedures utilizing state-of-the-art technology and best practices in gastroenterology. Dr. Sadeghi is highly experienced in performing endoscopic evaluations and minimally invasive interventions to accurately diagnose, monitor, and treat a full spectrum of digestive diseases.

• Colonoscopy and Colon Cancer Screening
• Upper Endoscopy (EGD)
• Flexible Sigmoidoscopy
• Advanced Endoscopic Techniques
• Imaging and Laboratory Testing
• Breath Tests for SIBO, H. pylori, and Lactose Intolerance
• Stool Studies and Microbiome Analysis

Scientific Approach: Gut Health, Microbiome, and Prevention

The gut microbiome—a complex ecosystem of over 100 trillion microorganisms—plays a central role in digestive health, immune regulation, and metabolic function. Disruptions in the microbiome are linked to a wide range of GI and systemic diseases. Dr. Sadeghi's practice emphasizes:

• Root Cause Analysis: Identifying underlying contributors to GI symptoms and disease, including microbiome imbalances, dietary factors, and metabolic dysfunction.
• Precision Medicine: Tailoring diagnostic and treatment strategies to each patient's unique genetic, metabolic, and lifestyle profile.
• Prevention and Disease Reversal: Focusing on early detection, risk factor modification, and evidence-based interventions to prevent progression and recurrence of GI disease.
• Nutrition and Lifestyle Optimization: Guiding patients toward plant-predominant, high-fiber diets and sustainable lifestyle changes that support gut health and reduce inflammation. This approach is grounded in current scientific evidence linking nutrition and the microbiome to digestive and overall health see: NIH Human Microbiome Project.

Why Choose Dr. Angie Sadeghi, MD?

Board-Certified Expertise and Patient-Centered Care

Dr. Angie Sadeghi is a board-certified gastroenterologist and internist with over 22 years of clinical experience. She is recognized for her advanced skills in endoscopic procedures, complex GI diagnosis, and her commitment to integrating nutrition and lifestyle medicine into digestive care. Dr. Sadeghi is the founder of IOPBM in Newport Beach, where she leads a multidisciplinary team dedicated to comprehensive, personalized care.

Education and Training:

• MD, Ross University School of Medicine
• Internal Medicine and Gastroenterology Fellowships, LAC+USC Medical Center
• Board Certified, American Board of Gastroenterology (Doximity Profile)

Professional Memberships:

• American Gastroenterological Association
• American College of Gastroenterology

Media and Publications:

• Co-author, The Trifecta of Health (Amazon)
• Featured in Forks Over Knives, VegOut Magazine, and multiple health documentaries (Forks Over Knives Webinar)

Patient-Centered Philosophy:

• Known for her thorough, compassionate approach and dedication to empowering patients with knowledge and practical strategies for long-term health (U.S. News Profile).

Patient Reviews: Real Experiences in Digestive Health

Scott M. — May 5, 2025

"Dr. Angie was recommended to me after a torn intestine sent me to the ER where I spent 10 days in ICU and the hospital. From our first contact she and her staff have been amazing! Dr. Angie is very caring and responsive. She knew that there were underlying issues that contributed to my condition and was very determined in getting a correct diagnosis. She also stressed the need to change my lifestyle to become healthier. I am now part of her Institute of Plant-Based Medicine's Full and Fit Weight Loss Program and their concierge service. I have made a quick recovery from my surgery, lost weight, and I am feeling better than I have in a long while. Dr. Angie makes me feel like I am her only patient. She is very thorough and is always suggesting ways to help me improve my health. I have recommended Dr. Angie Sadeghi to friends and family. She is fantastic." - Yelp

Brad L. — Feb 13, 2025

"Been using Dr Sadeghi for years for colonoscopies & gut health. She literally saved my wife from needing colon surgery by using a special outpatient technique (repeated partial removals spaced 3 mo apart). More recently, I'm attending her health & weight loss program. She and her team of fitness and nutrition specialists are coaching me in avoiding becoming full diabetic, applying the principles of her book 'The Trifecta Of Health.' It's just been a week but I'm very motivated and feeling good about the path I'm on. She's also just a genuine pleasure to work with. Everything about her is positive." - Yelp

Mimi L. — Jan 14, 2025

"I saw Dr Sadeghi after the first GI doc—aka pompous jerk—had already diagnosed me from my paperwork before he met me. He had his diagnosis (which he never gave me), prescribed medication, and sent me on my way. I could not ask a question. If I did he cut me off. Forward to Dr Sadeghi. She spent the entire appointment grilling me about current gut issues, other health issues, and what I was doing now. She even asked, 'If I could do one thing for you what would it be?' She had me change the protocol I was using because nothing else worked to see how that goes and is ordering CT of gut and pelvis. First guy Abrahm couldn't even be bothered to make a follow-up appointment. I don't know how this will turn out but wow, first doc in a long time who listened to me and asked a million questions. I was so used to dumb docs I was giving her info and she would stop me saying she didn't need every detail—just broad strokes. She took charge and I liked that. I'm a little more hopeful that she can help me but man my gut is a mess." - Yelp

Our Multidisciplinary Team and Services

At IOPBM, patients benefit from a collaborative team of gastroenterologists, registered dietitian nutritionists, and psychologists. This multidisciplinary approach ensures comprehensive care for complex GI conditions, including:

• Medical Nutrition Therapy (MNT) for GI Disorders
• Weight Management Programs
• Psychological Support for GI–Mental Health Connections
• Cardiology and Internal Medicine Coordination
• Bioidentical Hormone Optimization for Metabolic Health

Frequently Asked Questions